RxArt, a not-for-profit corporation that bridges art and healing, has been on a mission to make hospital-staying more tolerable. It has brought an impressive roster of artists (assume vivid astro focus, Frank Stella, Fred Tomaselli, Laura Owens, Rob Pruitt, Ryan McGinness, Vito Acconci, Wolfgang Tillmans and William Wegman, just to name a few) to create on-site work and installations to cheer up little patients at children's hospitals around the country since 2002. This year, RxArt teamed up with artist Dan Colen on a 200-piece puzzle from a photo of chewed Bazooka bubble gum. They also made a more child-friendly version with only 35 pieces. A signed puzzle goes for $250 while unsigned ones are $75. You can also find last year's puzzle by Terry Richardson and other original works by artists like Rita Ackermann, Will Cotton and Jennifer Steinkamp at RxArt's online store.